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"HOPE" for Motion Sickness Sufferers?

Ask anybody whose vacation has been ruined by motion sickness: what would they do to avoid a
heaving stomach, sweaty palms, and the positively dreadful feeling of unrelenting nausea
during their next trip? The most likely answer that you may hear is a resounding
"ANYTHING THAT WORKS."
They'll buy wristbands promising acupressure to relieve the nausea. They'll pay
inflated prices at airport gift shops for over-the-counter remedies that make them sleepy.
They'll swill ginger tea by the gallon. They'll even attempt to ignore the motion by
concentrating on the unmoving horizon. In short, those who suffer motion sickness are
desperate for "ANYTHING THAT WORKS".
Vacations are intended to be special
times unrestrained by concerns of daily life. Exotic photos in travel brochures raise
expectations of excitement, enjoyment, and entertainment. However, vacations are
expensive. You do not pay money to become sick. Instead, you want to have fun. A product
that prevents motion sickness represents "trip insurance" to minimize unpleasant
interruptions in your travel pleasure.
NASA conducted a study comparing the
efficacy of 16 different motion sickness products and identified scopolamine as most
effective in preventing motion sickness in astronauts.
Scopolamine patch is available by
prescription in the United States in topical patches and low dose tablets. Both of these
products are indicated to prevent motion sickness.
Scopolamine patches (marketed as
Transderm Scop by Novartis in East Hanover, New Jersey) have been used by travelers
because of their relative ease of use and extended duration of effect. They are ideally
suited for average size persons (approximately 160 pounds) going on extended trips
involving continuous motion for up to 72 hours.
While the scopolamine patch is
effective for some travelers, the fixed dose of medication that it provides may not be
appropriate for all. A petite woman may require less medication than that fixed dose.
Conversely, a larger man may require more.
Why is dosing flexibility important?
In general, doctors recommend that you take as little medication as necessary to treat a
condition without getting undesired side effects. Too much scopolamine can make you drowsy
and cause dryness in the mouth. Too little would leave you vulnerable to developing motion
sickness. Tablets allow dosing flexibility so that you take as little as you need and
nothing more.
Another problem when medicine is
applied to the skin is that it may not penetrate the skin equally in all people. Skin
differs by thickness, coloring, hair patterns, and amounts of sweat produced. The patch
must first adhere to the skin in order for the medicine to penetrate the skin. Sometimes
it just falls off, especially on persons who are very sweaty. Even if it adheres to the
skin, there is a possibility that the medicine may not penetrate the skin. One published
clinical study reported that up to 27% of persons tested failed to absorb scopolamine
across the skin. So even if it is applied correctly, approximately one quarter of patients
who use the scopolamine patch may not get the medicine into their body and thereby be
unprotected from motion sickness.
This concern about absorption is not
present when taking scopolamine tablets (marketed as Scopace tablets by Hope
Pharmaceutials in Scottsdale, Arizona). Once swallowed, the tablet breaks apart quickly
and releases its medication for prompt absorption. The first dose should be taken an hour
prior to travel. Each dose provides up to 8 hours of travel comfort. With this in mind,
you can adjust the timing of each dose so that the medicine is working only when you need
it.
Furthermore, the size of each dose can
be adjusted with these tablets to ensure that you take an appropriate amount of medication
for your personal needs.
Scopace tablets are considerably less
expensive than the scopolamine patch. A survey of pharmacies reported dispensing prices of
under 30 cents per tablet. The actual cost to fill a prescription may even be less
because, as a prescription medication, this medication is frequently covered by health
insurance and not subject to sales tax.
You no longer need to avoid travel
because of concerns about motion sickness. Relief is available with effective,
prescription-strength medicine containing scopolamine.
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Motion Sickness:
What Works?
You selected the destination,
purchased the tickets, packed the bags, and loaded the car. You are ready for a wonderful
vacation, but do you have trip insurance? Not insurance from your travel agent; rather,
medicine from your doctor. Motion sickness can ruin a vacation with nausea and vomiting
that can make you feel miserable.
What causes motion sickness? Clinical
studies suggest that motion sickness arises when the brain receives conflicting signals
from sensory organs about the body's orientation. The conflict arises because the two main
position-sensing organs, our eyes and the cochlea in the inner ear, adjust at different
speeds when we are moved. Our eyes adjust immediately. The cochlea take longer. Until both
have adjusted and provide identical signals, confusion regarding the body's position may
occur and nausea may develop.
Everyone becomes nauseous if exposed
to sufficiently violent movements; however, some people are extremely susceptible.
Estimated at one third of the population, susceptible people are prone to develop moderate
to severe nausea even with only limited movement.
Debilitating physical symptoms of
motion sickness can disrupt travel. In very susceptible people, fear of motion sickness
will even preclude travel.
Motion sickness can be prevented.
Persons who develop mild conditions can obtain relief with over-the-counter drugs, herbal
remedies, and acupuncture-based devices. More potent prescription-strength medicine is
typically required by those who develop moderate to severe symptoms. A clinical study
conducted by NASA identified scopolamine as the most effective medication tested to
prevent motion sickness.
Scopolamine is available through
pharmacies by prescription in various dosage forms including low dose tablets (Scopace
tablets, marketed by Hope Pharmaceuticals). Each tablet dose provides up to 8 hours of
travel comfort. The typical dose is 1 or 2 tablets taken an hour before travel.
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